Reduced Lung-Cancer Mortality with Low-Dose CT Screening
Lung cancer continues to be the leading cause of cancer death, ahead of colorectal, breast, and prostate cancers. However, screening strategies have been comparatively limited. This landmark article demonstrates the use of low-dose CT to screen for lung cancer, and…
Thrombophilia Testing and Venous Thrombosis
Do patients with venous thrombosis require testing for inherited thrombophilia? Read the expert consensus in this review article. Here are some questions you should answer from this article: Why checking for inherited thrombophilia not clinically useful? What factors should determine…
Dyspnea after Bone Marrow Transplant: Recognize and Treat Graft-versus-Host Disease
Thank you Maralee for an interesting presentation of cough and dyspnea in a patient post-bone marrow transplant. What further work-up is indicated with this representative CT scan?
LMWH versus Warfarin for the Prevention of Recurrent VTE in Patients with Cancer (CLOT Trial)
Low-molecular-weight heparin (LMWH) rather than warfarin is routinely recommended for patients with venous thromboembolism (VTE) and active cancer. Much of that is based on this article. Think about these as you review the article: Clinical Question: In patients with cancer…
Hematology-Oncology
Educational Goals & Overview The goal of rotations in the intensive care unit is to train residents in the treatment and management of critical and complex patients. The rotations include an emphasis on procedural skills and competence in difficult conversations.
Acute Promyelocytic Leukemia
Thank you Dr. John Hollowed for an excellent presentation on acute promyelocytic leukemia
Teaching Points
- APL accounts for 5-20% of AML cases
- Increased incidence in people with prior cytotoxic therapy
- Presents with complications of pancytopenia, weakness, fatigue, infections, increased bruising/bleeding, DIC
- Diagnosis: bone marrow analysis and confirmation with PCR, FISH, or cytogenic analysis
- Treatment is All-trans Retinoic Acid (ATRA)
Pulmonary Squamous Cell Carcinoma
Thank you Dr. Annie Belzowski for an excellent presentation of pulmonary squamous cell carcinoma complicated by pulmonary abscess
Teaching Points
- Common causes of pulmonary abscess:
- Bacterial: Anaerobic bacteria, Pseudomonas aeruginosa, Mycobacteria
- Fungal: Aspergillus, Coccidioides, Histoplasma, Blastomyces, Cryptococcus
- Non-infectious: malignancy, embolism, vasculitis, scarcoidosis
- Clindamycin preferred agent, time course dependent on follow up imaging
- Common forms of lung cancer: adenocarcinoma (40%), small cell (15%), squamous cell (30%)
Oncology Clinic
Oncology clinic is held every Wednesday morning and afternoon in Clinic C.