Didactics – UCLA-Olive View Internal Medicine

Jan 04 2019

Effect of Spironolactone on Morbidity and Mortality in Patients with Severe Heart Failure

EBM, Landmark Research

Always think about optimizing CHAMP meds in patients with heart failure: ACE-inhibitor or ARB Beta-blocker Aspirin Statin Aldosterone antagonist for LVEF <35% Here's the evidence of use of spironolactone, a common aldosterone antagonist, in heart failure.

Clinical Topics:

Cardiology

Time-to-Furosemide Treatment and Mortality in Patients Hospitalized with Acute Heart Failure

EBM, Journal Club

Presented by Stephanie Wang, M.D.

Moderated by Matthew McCullough, M.D.

Key Discussion Points: Early treatment of acute heart failure with loop diuretics lowers mortality despite initial mortality risk, and this treatment strategy might be even more effective in high-risk AHF patients Earlier treatment/identification of acute heart failure relied heavily on…

Clinical Topics:

Eplerenone, a Selective Aldosterone Blocker, in Patients with Left Ventricular Dysfunction after Myocardial Infarction (EPHESUS Trial)

EBM, Landmark Research

Archive of Didactics in cardiomyopathy

Effect of Spironolactone on Morbidity and Mortality in Patients with Severe Heart Failure

Clinical Topics:

Time-to-Furosemide Treatment and Mortality in Patients Hospitalized with Acute Heart Failure

Clinical Topics:

Eplerenone, a Selective Aldosterone Blocker, in Patients with Left Ventricular Dysfunction after Myocardial Infarction (EPHESUS Trial)

Clinical Topics:

Medical School

Residency

Fellowship