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All-trans-Retinoic Acid (ATRA) in Acute Promyelocytic Leukemia (APML)

ATRA—short for all-trans retinoic acid—is an important component of initial treatment of acute promyelocytic leukemia (APML).  This article demonstrates the specific benefit of using this medication along with chemotherapy.

Things to think about while digging into this article:

  • How is APML diagnosed and what characteristic lab and genetic findings distinguish it from other acute myeloid leukemias?
  • What outcome does ATRA improve?

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