All-trans-Retinoic Acid (ATRA) in Acute Promyelocytic Leukemia (APML)
ATRA—short for all-trans retinoic acid—is an important component of initial treatment of acute promyelocytic leukemia (APML). This article demonstrates the specific benefit of using this medication along with chemotherapy. Things to think about while digging into this article: How is…
AM Report: ITP
In today's morning report, Dr. Gold presented a case of gum bleeding and fatigue in a young patient who was ultimately found to have severe thrombocytopenia secondary to ITP. Some pearls: There are lots of reasons to have low platelets,…
Morning Report: Pancytopenia
Thanks to future chief Dr. Hossain for a great learning case of a patient with pancytopenia secondary to pernicious anemia resulting in vitamin B12 deficiency. Key learning points: Vitamin B12 (cobalamin) is needed in the formation of hematopoietic cells. Deficiency…
Morning Report – Multiple Myeloma
Thank you Dr. Kahn for an interesting case of multiple myeloma in a patient presenting with chest pain. Key Learning Points: Keep your chest pain differential broad and always look for the sinister 6 (emergency) causes of chest pain (ACS,…
Morning Report: Pernicious Anemia
Thank you Dr. Kumar for an excellent case presentation on vitamin B12 deficiency secondary to pernicious anemia in a patient with Graves' disease and Vitiligo. Key Learning Points: Remember: B12 (cobalamin) levels are neither sensitive nor specific for the diagnosis…