Role of Echocardiography in Evaluation of Patient with S aureus Bacteremia
EBM, Landmark Research
Fluoxetine for Motor Recovery After Acute Ischaemic Stroke (FLAME): A Randomised Placebo-controlled Trial
EBM, Journal Club
Clinical Question: Can adding fluoxetine to standard therapy for ischemic stroke improve recovery from motor deficits?
Einstein Choice: Rivaroxaban or Aspirin for Extended Treatment of Venous Thromboembolism
EBM, Journal Club
Clinical Question In patients who would benefit from continued anti-coagulation is treatment dose rivaroxaban vs thromboprophylactic dose as effective as aspirin for prevention of recurrent thromboembolism? Bottom Line Rivaroxaban at both treatment dose (20mg) and a thromboprophylactic dose (10mg), was…
PESIT Trial
EBM, Journal Club
Thank you Dr. Noah Duncan for an excellent overview of the PESIT trial (Prevalence of Pulmonary Embolism among Patients Hospitalized for Syncope) Conclusions of the study: Pulmonary embolism was identified in nearly one of every 6 patients hospitalized for a…
Acute Promyelocytic Leukemia
Morning Report
Thank you Dr. John Hollowed for an excellent presentation on acute promyelocytic leukemia
Teaching Points
- APL accounts for 5-20% of AML cases
- Increased incidence in people with prior cytotoxic therapy
- Presents with complications of pancytopenia, weakness, fatigue, infections, increased bruising/bleeding, DIC
- Diagnosis: bone marrow analysis and confirmation with PCR, FISH, or cytogenic analysis
- Treatment is All-trans Retinoic Acid (ATRA)
Huntington’s Disease
Morning Report
Thank you Dr. Liza Buchbinder for an excellent presentation on Huntington’s Disease
Teaching Points
- Etiology: Autosomal dominant; Drug induced (antipsychotics, estrogen containing); Endocrine (thyrotoxicosis, hyperglycemia); pregnancy (chorea gravidarum); streptococcal infection (Sydenham chorea); autoimmune (SLE, APLS); neurodegenerative d/o of basal ganglia.
- Associated w/ parkinsonism, impulsiveness, psychiatric disorders, and dementia.
- Treatment is symptomatic
Narrow Complex Tachycardia
Noon Conference
TCA Induced Cardiotoxicity
Morning Report
Thank you Dr. Daniel Jimenez for an excellent presentation on TCA induced cardiotoxicity Teaching Points Clinical presentation: anticholinergic sx (urinary retention, constipation), CNS (seizures, coma), acidosis, arrythmias ECG: prolonged QRS/PR/QT --> predisposes for ventricular arrhythmias) Management: supportive care, benzos for seizures,…
BRIDGE TRIAL
EBM, Journal Club
Thank you Thomas Vu for your excellent overview of the BRIDGE trial (Perioperative Bridging Anticoagulation in Patients with Atrial Fibrillation) Conclusions of the study: In patients with atrial fibrillation who had warfarin treatment interrupted for an elective operation or other elective invasive…