Rosuvastatin to Prevent Vascular Events (JUPITER)
EBM, Landmark Research
This post is protected. Please log in to view content.
Clinical Trial of the Effects of Dietary Patterns on Blood Pressure (DASH)
EBM, Landmark Research
Hypertension—one of the top chronic conditions we face— involves a multipronged approach to management. In addition to pharmacotherapy, never forget to start with lifestyle modifications. Here we review the Dietary Approach to Stop Hypertension, from which the combination DASH diet…
Mild Therapeutic Hypothermia to Improve the Neurologic Outcome after Cardiac Arrest
EBM, Landmark Research
Effect of Spironolactone on Morbidity and Mortality in Patients with Severe Heart Failure
EBM, Landmark Research
Always think about optimizing CHAMP meds in patients with heart failure: ACE-inhibitor or ARB Beta-blocker Aspirin Statin Aldosterone antagonist for LVEF <35% Here's the evidence of use of spironolactone, a common aldosterone antagonist, in heart failure.
POET Trial: Partial Oral versus Intravenous Antibiotic Treatment of Endocarditis
EBM, Journal Club
Clinical Question: In clinically stable patients with endocarditis, does a shift from IV to PO administration of antibiotics result in similar efficacy and safety when compared to continued IV antibiotic therapy?
Comparison of carvedilol and metoprolol on clinical outcomes in patients with CHF (COMET)
EBM, Landmark Research
Clinical Question: What is the effect of carvedilol vs metoprolol tartrate on mortality and morbidity in patients with heart failure with reduced ejection fraction (HFrEF) and NYHA class II-IV symptoms? Take Away: In patients with HFrEF, carvedilol reduces all-cause mortality…
A Comparison of Rate Control and Rhythm Control in Patients with Atrial Fibrillation (AFFIRM)
EBM, Landmark Research
Rate control over rhythm control - that's the fundamental principle in treatment of atrial fibrillation, and here's the why we do this. Read the landmark article below and as a group, review the presentation here on TrialGuru.org.
Prasugrel versus Clopidogrel in Patients with Acute Coronary Syndromes
EBM, Landmark Research
Antagonists of the P2Y12 ADP receptor, in addition to aspirin, are the mainstay of treatment of non-ST elevation acute coronary syndromes (NSTE-ACS). Although Clopidogrel (Plavix®) has been widely used for years, newer agents have come into use, including Ticagrelor (Brilinta®) and Prasugrel…
Chagas Disease: A Review for the Global Health Elective
Chagas Disease is endemic to Mexico, Central America, and South America, with an estimated 8 million people infected, according to the CDC. Chronic manifestations are not uncommonly seen at Olive View due to immigration from endemic areas, and the Center…