Morbidity & Mortality: Heparin Drips
Morbidity & Mortality, Morning Report
Thrombophilia Testing and Venous Thrombosis
EBM, Landmark Research
Do patients with venous thrombosis require testing for inherited thrombophilia? Read the expert consensus in this review article. Here are some questions you should answer from this article: Why checking for inherited thrombophilia not clinically useful? What factors should determine…
Acute Promyelocytic Leukemia
Morning Report
Thank you Dr. John Hollowed for an excellent presentation on acute promyelocytic leukemia
Teaching Points
- APL accounts for 5-20% of AML cases
- Increased incidence in people with prior cytotoxic therapy
- Presents with complications of pancytopenia, weakness, fatigue, infections, increased bruising/bleeding, DIC
- Diagnosis: bone marrow analysis and confirmation with PCR, FISH, or cytogenic analysis
- Treatment is All-trans Retinoic Acid (ATRA)