Today's morning report case focused on a patient with poorly controlled diabetes who presented with non-productive cough for several months and was found to have a large RUL heterogeneous consolidation secondary to pulmonary Cryptococcosis. Take a look at some of…
Aspergillus is extremely common in the environment (think black mold), but only rarely causes invasive infection particularly with severe immunosuppression: immunosuppressive therapy, e.g. for acute leukemia, hematopoietic stem cell and solid organ transplant severe, prolonged neutropenia high-dose, prolonged glucocorticoid use…
Dr. Refugio presented a classic case of Pneumocystis jirovecci pneumonia (PJP) in a patient with newly diagnosed HIV. Here are some important learning points: The classic presenting symptoms for PJP are fever, non-productive cough, and progressive dyspnea Most cases occur…
The mainstay of treatment for bacterial meningitis are: High-dose IV antibiotics: Ceftriaxone, Vancomycin, +/- Ampicillin Steroids Patient isolation Here's the evidence for using steroids in bacterial meningitis.
Clinical Question: In clinically stable patients with endocarditis, does a shift from IV to PO administration of antibiotics result in similar efficacy and safety when compared to continued IV antibiotic therapy?
Current antibiotic stewardship guidelines at Olive View recommend 4 days of antibiotics for intraabdominal infections once source control is achieved. Here is clinical evidence of this "short" duration of antibiotics.
CURB-65: the easy-to-use clinical prediction rule helps us triage patients with pneumonia to inpatient or outpatient care. What is this actually based upon? This is the original study used to develop the CURB-65. Here are some things to think about…
The optimal duration of antibiotic treatment for ventilator-associated pneumonia (VAP) is not known. Shortening the course of therapy may help decrease antibiotic resistance and adverse effects of giving prolonged antibiotics. This study looks to establish that mortality and recurrent infections…
