Prophylactic Implantation of a Defibrillator in Patients with Myocardial Infarction and Reduced Ejection Fraction (MADIT-II)
In this article, we review how prophylactic implantation of defibrillator decreases mortality in patients with advanced LV dysfunction following prior MI.
Validation and Refinement of Scores to Predict Very Early Stroke Risk after TIA
When encountering patients with TIA, how do you decide to admit or not admit? The reason for admission should include those patients at high risk for stroke. So how do you risk stratify TIA patients? The ABCD2 score is a…
All-trans-Retinoic Acid (ATRA) in Acute Promyelocytic Leukemia (APML)
ATRA—short for all-trans retinoic acid—is an important component of initial treatment of acute promyelocytic leukemia (APML). This article demonstrates the specific benefit of using this medication along with chemotherapy. Things to think about while digging into this article: How is…
Prednisolone in Patients with Severe Alcoholic Hepatitis
Rivaroxaban versus Warfarin in Nonvalvular Atrial Fibrillation (ROCKET-AF)
Therapies for Active Rheumatoid Arthritis after Methotrexate Failure
Voriconazole Versus Amphotericin B for Primary Therapy of Invasive Aspergillosis
Aspergillus is extremely common in the environment (think black mold), but only rarely causes invasive infection particularly with severe immunosuppression: immunosuppressive therapy, e.g. for acute leukemia, hematopoietic stem cell and solid organ transplant severe, prolonged neutropenia high-dose, prolonged glucocorticoid use…