Rivaroxaban versus Warfarin in Nonvalvular Atrial Fibrillation (ROCKET-AF)
EBM, Landmark Research
Therapies for Active Rheumatoid Arthritis after Methotrexate Failure
EBM, Landmark Research
Voriconazole Versus Amphotericin B for Primary Therapy of Invasive Aspergillosis
EBM, Landmark Research
Aspergillus is extremely common in the environment (think black mold), but only rarely causes invasive infection particularly with severe immunosuppression: immunosuppressive therapy, e.g. for acute leukemia, hematopoietic stem cell and solid organ transplant severe, prolonged neutropenia high-dose, prolonged glucocorticoid use…
Randomized Trial of Colchicine for Acute Pericarditis
EBM, Landmark Research
Let's review: General treatment options for acute pericarditis include: NSAID's Colchicine Prednisone Read this article to learn which agent or combination of agents has more benefit.
Strategies for Multivessel Revascularization in Patients with Diabetes (FREEDOM)
EBM, Landmark Research
What treatment is recommend for diabetic patients with 3-vessel coronary artery disease? Review this landmark article to find the evidence for multivessel CAD treatment recommendations in diabetes.
4-Year Trial of Tiotropium in Chronic Obstructive Pulmonary Disease (UPLIFT)
EBM, Landmark Research
Thrombolysis with Alteplase 3 to 4.5 Hours after Acute Ischemic Stroke (ECASS III)
EBM, Landmark Research
Time is tissue—and the brain is no exception. Here's the landmark article guiding our use of thombolytics within 4.5 hours of an acute stroke. Remember, the clock starts ticking from the patient's last well-known time, not from the time of…
Initial Treatment of ITP with High-Dose Dexamethasone
EBM, Landmark Research
Rosuvastatin to Prevent Vascular Events (JUPITER)
EBM, Landmark Research
This post is protected. Please log in to view content.
Tolvaptan, a Selective Oral Vasopressin V2-Receptor Antagonist, for Hyponatremia
EBM, Landmark Research
Dig deep for that kidney knowledge! Let's quickly review: Arginine vasopressin, otherwise known as antidiuretic hormone (ADH), acts on V2 receptors in the renal distal convoluted tubules to concentrate the urine to maintain water homeostasis. It is implicated in the…