Antithrombotic Therapy for Atrial Fibrillation with Stable Coronary Disease (AFIRE)
Thank you Nikita for leading us through a discussion of the AFIRE trial.
Clinical Question:
In patients with atrial fibrillation and stable CAD >1 year after revascularization (or confirmed CAD on angiography not requiring revascularization), how does rivaroxaban monotherapy compare to rivaroxaban plus an antiplatelet agent in terms of efficacy and safety?
Prophylactic Implantation of a Defibrillator in Patients with Myocardial Infarction and Reduced Ejection Fraction (MADIT-II)
In this article, we review how prophylactic implantation of defibrillator decreases mortality in patients with advanced LV dysfunction following prior MI.
Validation and Refinement of Scores to Predict Very Early Stroke Risk after TIA
When encountering patients with TIA, how do you decide to admit or not admit? The reason for admission should include those patients at high risk for stroke. So how do you risk stratify TIA patients? The ABCD2 score is a…
All-trans-Retinoic Acid (ATRA) in Acute Promyelocytic Leukemia (APML)
ATRA—short for all-trans retinoic acid—is an important component of initial treatment of acute promyelocytic leukemia (APML). This article demonstrates the specific benefit of using this medication along with chemotherapy. Things to think about while digging into this article: How is…