Rivaroxaban versus Warfarin in Nonvalvular Atrial Fibrillation (ROCKET-AF)
Therapies for Active Rheumatoid Arthritis after Methotrexate Failure
Voriconazole Versus Amphotericin B for Primary Therapy of Invasive Aspergillosis
Aspergillus is extremely common in the environment (think black mold), but only rarely causes invasive infection particularly with severe immunosuppression: immunosuppressive therapy, e.g. for acute leukemia, hematopoietic stem cell and solid organ transplant severe, prolonged neutropenia high-dose, prolonged glucocorticoid use…
Randomized Trial of Colchicine for Acute Pericarditis
Let's review: General treatment options for acute pericarditis include: NSAID's Colchicine Prednisone Read this article to learn which agent or combination of agents has more benefit.
Strategies for Multivessel Revascularization in Patients with Diabetes (FREEDOM)
What treatment is recommend for diabetic patients with 3-vessel coronary artery disease? Review this landmark article to find the evidence for multivessel CAD treatment recommendations in diabetes.
4-Year Trial of Tiotropium in Chronic Obstructive Pulmonary Disease (UPLIFT)
Thrombolysis with Alteplase 3 to 4.5 Hours after Acute Ischemic Stroke (ECASS III)
Time is tissue—and the brain is no exception. Here's the landmark article guiding our use of thombolytics within 4.5 hours of an acute stroke. Remember, the clock starts ticking from the patient's last well-known time, not from the time of…
Initial Treatment of ITP with High-Dose Dexamethasone
