Dig deep for that kidney knowledge! Let's quickly review: Arginine vasopressin, otherwise known as antidiuretic hormone (ADH), acts on V2 receptors in the renal distal convoluted tubules to concentrate the urine to maintain water homeostasis. It is implicated in the…
Hypertension—one of the top chronic conditions we face— involves a multipronged approach to management. In addition to pharmacotherapy, never forget to start with lifestyle modifications. Here we review the Dietary Approach to Stop Hypertension, from which the combination DASH diet…
Always think about optimizing CHAMP meds in patients with heart failure: ACE-inhibitor or ARB Beta-blocker Aspirin Statin Aldosterone antagonist for LVEF <35% Here's the evidence of use of spironolactone, a common aldosterone antagonist, in heart failure.
The mainstay of treatment for bacterial meningitis are: High-dose IV antibiotics: Ceftriaxone, Vancomycin, +/- Ampicillin Steroids Patient isolation Here's the evidence for using steroids in bacterial meningitis.
This classic, often-cited article informs us that among patients in the ICU, intensive glucose control of 81-108 increased mortality as compared to a more liberal glucose target of <180. How have you applied the findings of this research to your…
This article helps us to answer: What is the effect of early introduction of palliative care to ambulatory patients soon after diagnosis of metastatic non-small-cell lung cancer (NSCLC) on quality of life outcomes and end-of-life care?
Clinical Question: In clinically stable patients with endocarditis, does a shift from IV to PO administration of antibiotics result in similar efficacy and safety when compared to continued IV antibiotic therapy?