Do patients with venous thrombosis require testing for inherited thrombophilia? Read the expert consensus in this review article. Here are some questions you should answer from this article: Why checking for inherited thrombophilia not clinically useful? What factors should determine…
Patients with progressive chronic kidney disease are typically initiated on hemodialysis at CKD Stage 5. But is there benefit to starting it earlier versus later in Stage 5. This studies compares initiation of hemodialysis at eGFR 10-15 versus 5-7. Here…
What role do corticosteroids have in acute infection, particularly in pneumonia requiring hospitalization? This study from Switzerland argues there might be some benefits. As you can imagine, there is some controversy about the use of steroids.
Here are some questions to think about as you review this study: What adverse events were associated with the use of atorvastatin? Are these results externally valid and applicable to your patients diagnosed with ischemic stroke or TIA? How was…
Do you ever give NSAID’s to patients with cardiomyopathy? Usually not, and here is evidence supporting why we don’t. But are there some NSAID’s that have less unfavorable outcomes?
Lactulose is widely used for treatment of hepatic encephalopathy because it is effective, cheap, and widely available. So is there any benefit to using Rifaximin in patients with hepatic encephalopathy? Here are some questions to answer when reviewing this article…
Low-molecular-weight heparin (LMWH) rather than warfarin is routinely recommended for patients with venous thromboembolism (VTE) and active cancer. Much of that is based on this article. Think about these as you review the article: Clinical Question: In patients with cancer…
Thank you, Alex, for a review of outcome data for one of the newest diabetes medications: canaglifozin (Invokana®). Canaglifozin is a SGLT2 inhibitor, which decreases reabsorption of glucose in the renal tubules. Clinical Question: Among patients with DM2 at high risk…